Article
[Relationship between Polymorphism in ALOX5, ALOX5AP and Susceptibility to Myeloid Leukemia].
Zhongguo shi yan xue ye xue za zhi - 1 Feb 2020
Mei Fen, Wang Yan-Fei, Yang Dan, Zuo Rong-Xia, Shen Tao, Yang Tong-Hua, Sa Ya-Lian
Abstract excerpt
OBJECTIVE: To investigate the correlation of single nucleotide polymorphisms (SNP) in arachidonate 5-lipoxygenase gene (ALOX5) rs2029253, rs2228064 and rs2228065 sites, 5-lipoxygenase activating protein gene (ALOX5AP) rs10507391, rs4769874 sites with the risk for genesis of adult myeloid leukemia. METHODS: By the approval from the hospital ethics committee and the informed consent of participants. 150 patients...
