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Article

Polymorphisms in microRNA target sites modulate risk of lymphoblastic and myeloid leukemias and affect microRNA binding.

Journal of hematology & oncology - 2 Jun 2014

Dzikiewicz-Krawczyk Agnieszka, Macieja Anna, Mały Ewa, Januszkiewicz-Lewandowska Danuta, Mosor Maria, Fichna Marta, Strauss Ewa, Nowak Jerzy

Abstract excerpt

BACKGROUND: MicroRNA dysregulation is a common event in leukemia. Polymorphisms in microRNA-binding sites (miRSNPs) in target genes may alter the strength of microRNA interaction with target transcripts thereby affecting protein levels. In this study we aimed at identifying miRSNPs associated with leukemia risk and assessing impact of these miRSNPs on miRNA binding to target transcripts. METHODS: We analyzed with...

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Identifiers

PMID: 24886876
DOI: 10.1186/1756-8722-7-43
PMCID: PMC4059877

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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