Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Regulation of PINK1-Parkin-mediated mitophagy

8 Feb 2011

Abstract excerpt

Parkinson disease (PD) is a devastating disorder of the nervous system for which no cure exists. Although the exact mechanisms involved in the pathogenesis of PD are unclear, very recently, a novel cellular process has been identified that promises great future potential. Two PD-associated genes have been found to converge on the emerging mitophagy pathway that links the two major cellular dysfunctions implicated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Parkinson's Disease Mechanisms and Treatments

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 21187721
DOI: 10.4161/auto.7.3.14348

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Regulation of PINK1-Parkin-mediated mitophagyPMID 21187721Read ↗

Mitophagy in Parkinson’s Disease: From Pathogenesis to TreatmentSemantic proximity Read ↗

Mitophagy and Parkinson's disease: The PINK1–parkin linkSemantic proximity Read ↗

PINK1/Parkin-mediated mitophagy in neurodegenerative diseasesSemantic proximity Read ↗

Parkin- and PINK1-Dependent Mitophagy in Neurons: Will the Real Pathway Please Stand Up?Semantic proximity Read ↗

PINK1 and Parkin: emerging themes in mitochondrial homeostasisSemantic proximity Read ↗

Disruption of Mitochondrial Homeostasis: The Role of PINK1 in Parkinson’s DiseaseSemantic proximity Read ↗

PINK1, Parkin, and Mitochondrial Quality Control: What can we Learn about Parkinson’s Disease Pathobiology?Semantic proximity Read ↗

PINK1/Parkin mitophagy and neurodegeneration—what do we really know in vivo?Semantic proximity Read ↗

PINK1/Parkin-Dependent Mitochondrial Surveillance: From Pleiotropy to Parkinson's DiseaseSemantic proximity Read ↗

Hallmarks and Molecular Tools for the Study of Mitophagy in Parkinson’s DiseaseSemantic proximity Read ↗

PINK1-parkin-dependent mitophagy involves ubiquitination of mitofusins 1 and 2: Implications for Parkinson disease pathogenesisSemantic proximity Read ↗

Defective PTEN-induced kinase 1/Parkin mediated mitophagy and neurodegenerative diseasesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.