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Article

Scavenger receptor class B type I is more conducive for genotype 1b hepatitis C virus internalization than low-density lipoprotein receptor.

Acta virologica - 1 Jan 2021

Cao Xiangyi, Kang Qiong, Deng Jiang, Xiao Jun, Zhang Yanyu, Ma Ping, Yang Xiaoang, Lv Liping

Abstract excerpt

The current limited understanding of HCV entry mechanisms hinders the development of specific antiviral drug screening techniques and vaccine assessment. HCV subtypes and cellular surface proteins both can affect virus tropism. Human factors such as low-density lipoprotein receptor (hLDLR), CD81 (hCD81), scavenger receptor class B type I (hSR-BI), claudin 1 (hCLDN1), and occludin (hOCLN) assist HCV entry into...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34565156
DOI: 10.4149/av_2021_307

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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