Article
Role of high-risk variants in the development of impaired glucose metabolism was modified by birth weight in Han Chinese.
Diabetes/metabolism research and reviews - 1 Nov 2015
Zhang Yun, Xiao Xinhua, Zhang Zhenxin, Ma Xuejun, Xu Tao, Li Wenhui, Feng Kai, Sun Qi, Zhang Qian
Abstract excerpt
BACKGROUND: The aim of this study was to investigate the role of common variants in the genes SLC30A8, KCNQ1, and TCF7L2 in the association between birth weight and increased risk of type 2 diabetes in Han Chinese. METHODS: Seven variants (SLC30A8-rs13266634 and rs2466293; KCNQ1-rs2237895 and rs2074196; and TCF7L2-rs11196218, , and ) were genotyped in 1181 individuals born in Peking Union Medical...
