Article
Low birthweight and risk of type 2 diabetes: a Mendelian randomisation study.
Diabetologia - 1 Sept 2016
Wang Tiange, Huang Tao, Li Yanping, Zheng Yan, Manson JoAnn E, Hu Frank B, Qi Lu
Abstract excerpt
AIMS/HYPOTHESIS: Low birthweight has been associated with a high risk of type 2 diabetes mellitus in observational studies. However, it remains unclear whether this relation is causal. METHODS: The present study included 3627 individuals with type 2 diabetes and 12,974 control participants of European ancestry from the Nurses' Health Study and the Health Professionals Follow-Up Study. A genetic risk score (GRS)...
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