Low birthweight and risk of type 2 diabetes: a Mendelian randomisation study.

doi:10.1007/s00125-016-4019-z

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Low birthweight and risk of type 2 diabetes: a Mendelian randomisation study.

Diabetologia - 1 Sept 2016

Wang Tiange, Huang Tao, Li Yanping, Zheng Yan, Manson JoAnn E, Hu Frank B, Qi Lu

Abstract excerpt

AIMS/HYPOTHESIS: Low birthweight has been associated with a high risk of type 2 diabetes mellitus in observational studies. However, it remains unclear whether this relation is causal. METHODS: The present study included 3627 individuals with type 2 diabetes and 12,974 control participants of European ancestry from the Nurses' Health Study and the Health Professionals Follow-Up Study. A genetic risk score (GRS)...

Topics

Adenylyl Cyclases
Adult
Aged
Birth Weight
Diabetes Mellitus, Type 2
Female
Genetic Predisposition to Disease
Genome-Wide Association Study
Genotype
Humans
Infant, Low Birth Weight
Male
Mendelian Randomization Analysis
Middle Aged

Source

Open in PubMed Open full text

Identifiers

PMID: 27333884
DOI: 10.1007/s00125-016-4019-z
PMCID: PMC4970938

Genes

CCNL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Risk Factors

Software

White People