Association of SNPs with the efficacy and safety of immunosuppressant therapy after heart transplantation.

doi:10.2217/pgs.15.39

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Article

Association of SNPs with the efficacy and safety of immunosuppressant therapy after heart transplantation.

Pharmacogenomics - 1 Jan 2015

Sánchez-Lázaro Ignacio, Herrero María José, Jordán-De Luna Consuelo, Bosó Virginia, Almenar Luis, Rojas Luis, Martínez-Dolz Luis, Megías-Vericat Juan E, Sendra Luis, Miguel Antonio, Poveda José L, Aliño Salvador F

Abstract excerpt

AIM: Studying the possible influence of SNPs on efficacy and safety of calcineurin inhibitors upon heart transplantation. MATERIALS & METHODS: In 60 heart transplant patients treated with tacrolimus or cyclosporine, we studied a panel of 36 SNPs correlated with a series of clinical parameters during the first post-transplantation year. RESULTS: The presence of serious infections was correlated to ABCB1 rs1128503...

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PMID: 26107754
DOI: 10.2217/pgs.15.39

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ABCB1
NOD2

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