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Article

Utilization of an EMR-biorepository to identify the genetic predictors of calcineurin-inhibitor toxicity in heart transplant recipients.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 2014

Oetjens Matthew, Bush William S, Birdwell Kelly A, Dilks Holli H, Bowton Erica A, Denny Joshua C, Wilke Russell A, Roden Dan M, Crawford Dana C

Abstract excerpt

Calcineurin-inhibitors CI are immunosuppressive agents prescribed to patients after solid organ transplant to prevent rejection. Although these drugs have been transformative for allograft survival, long-term use is complicated by side effects including nephrotoxicity. Given the narrow therapeutic index of CI, therapeutic drug monitoring is used to prevent acute rejection from underdosing and acute toxicity from...

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PMID: 24297552
PMCID: PMC3923429

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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