Article
Pharmacogenetics in solid organ transplantation: current status and future directions.
Transplantation reviews (Orlando, Fla.) - 1 Jan 2008
de Jonge Hylke, Kuypers Dirk R J
Abstract excerpt
Tailoring of immunosuppressive drug therapy to the specific requirements of the individual patient to optimize efficacy and minimize toxicity remains one of the biggest challenges in solid organ transplantation. Pharmacogenetic and pharmacogenomic research, studying the effects of genetic polymorphisms on drug disposition and action, holds promise to produce useful clinical tools for individualizing...
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