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Article

FKBP-CaN-NFAT pathway polymorphisms selected by in silico biological function prediction are associated with tacrolimus efficacy in renal transplant patients.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences - 1 May 2021

Zheng Xinyi, Huai Cong, Xu Qinxia, Xu Luyang, Zhang Ming, Zhong Mingkang, Qiu Xiaoyan

Abstract excerpt

AIM: The aim of the present study was to investigate the potential effects of genetic variations in the FKBP-CaN-NFAT pathway on clinical events associated with tacrolimus efficacy in Chinese renal transplant patients. METHODS: One hundred and forty Chinese renal transplant patients of Han ethnicity with over five years of follow-up were enrolled in our study. A pool of single nucleotide polymorphisms (SNPs)...

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PMID: 33383132
DOI: 10.1016/j.ejps.2020.105694

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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