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Article

Melanocortin 1 receptor variants and skin cancer risk.

International journal of cancer - 15 Oct 2006

Han Jiali, Kraft Peter, Colditz Graham A, Wong Jason, Hunter David J

Abstract excerpt

Melanocortin 1 receptor (MC1R) gene variants are associated with red hair and fair skin color. We assessed the associations of common MC1R genotypes with the risks of 3 types of skin cancer simultaneously in a nested case-control study within the Nurses' Health Study (219 melanoma, 286 squamous cell carcinoma (SCC), and 300 basal cell carcinoma (BCC) cases, and 873 controls). We found that the 151Cys, 160Trp and...

Topics

Adult
Aged
Case-Control Studies
Color
Female
Genetic Variation
Genotype
Hair
Haplotypes
Humans
Middle Aged
Receptor, Melanocortin, Type 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Risk Factors

Skin Neoplasms

Sunlight

Source

Identifiers

PMID: 16721784
DOI: 10.1002/ijc.22074

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Melanocortin 1 receptor variants and skin cancer risk.PMID 16721784Read ↗

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MC1R gene variants and non-melanoma skin cancer: a pooled-analysis from the M-SKIP project.Semantic proximity Read ↗

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Melanocortin 1 receptor (MC1R) gene variants are associated with an increased risk for cutaneous melanoma which is largely independent of skin type and hair color.Semantic proximity Read ↗

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