Article

Leveraging lung tissue transcriptome to uncover candidate causal genes in COPD genetic associations

2017-09-26

Abstract excerpt

<h4>ABSTRACT</h4> We collated 129 non-overlapping risk loci for chronic obstructive pulmonary disease (COPD) from the GWAS literature. Using recent and complementary integrative genomics approaches, combining GWAS and lung eQTL results, we identified 12 novel COPD loci and corresponding causal genes. In addition, we mapped candidate causal genes for 60 out of the 129 GWAS-nominated loci as well as for four sub-ge...

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Literature Corpus work: d082d4dd-cc5f-53ff-a944-a91e118628ce
DOI: 10.1101/193938

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