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Association of asthma genetic variants with asthma‐associated traits reveals molecular pathways of eosinophilic asthma

1 Apr 2023

Abstract excerpt

INTRODUCTION: Asthma is a complex, polygenic, heterogenous inflammatory disease. Recently, we generated a list of 128 independent single nucleotide polymorphisms (SNPs) associated with asthma in genome-wide association studies. However, it is unknown if asthma SNPs are associated with specific asthma-associated traits such as high eosinophil counts, atopy, and airway obstruction, revealing molecular endotypes of...

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PMID: 37186423
DOI: 10.1002/clt2.12239

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