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Article

FOXM1 binds directly to non-consensus sequences in the human genome.

Genome biology - 23 Jun 2015

Sanders Deborah A, Gormally Michael V, Marsico Giovanni, Beraldi Dario, Tannahill David, Balasubramanian Shankar

Abstract excerpt

BACKGROUND: The Forkhead (FKH) transcription factor FOXM1 is a key regulator of the cell cycle and is overexpressed in most types of cancer. FOXM1, similar to other FKH factors, binds to a canonical FKH motif in vitro. However, genome-wide mapping studies in different cell lines have shown a lack of enrichment of the FKH motif, suggesting an alternative mode of chromatin recruitment. We have investigated the role...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26100407
DOI: 10.1186/s13059-015-0696-z
PMCID: PMC4492089

Genes

FOXM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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