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Article

Molecular determinants of the cell-cycle regulated Mcm1p-Fkh2p transcription factor complex.

Nucleic acids research - 1 May 2003

Boros Joanna, Lim Fei-Ling, Darieva Zoulfia, Pic-Taylor Aline, Harman Ruth, Morgan Brian A, Sharrocks Andrew D

Abstract excerpt

The MADS-box transcription factor Mcm1p and forkhead (FKH) transcription factor Fkh2p act in a DNA-bound complex to regulate cell-cycle dependent expression of the CLB2 cluster in Saccharomyces cerevisiae. Binding of Fkh2p requires prior binding by Mcm1p. Here we have investigated the molecular determinants governing the formation of the Mcm1p- Fkh2p complex. Fkh2p exhibits cooperativity in complex formation with...

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Identifiers

PMID: 12711672
DOI: 10.1093/nar/gkg347
PMCID: PMC154233

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SRF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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