The role of HPV RNA transcription, immune response-related gene expression and disruptive TP53 mutations in diagnostic and prognostic profiling of head and neck cancer.

doi:10.1002/ijc.29649

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Article

The role of HPV RNA transcription, immune response-related gene expression and disruptive TP53 mutations in diagnostic and prognostic profiling of head and neck cancer.

International journal of cancer - 15 Dec 2015

Wichmann Gunnar, Rosolowski Maciej, Krohn Knut, Kreuz Markus, Boehm Andreas, Reiche Anett, Scharrer Ulrike, Halama Dirk, Bertolini Julia, Bauer Ulrike, Holzinger Dana, Pawlita Michael, Hess Jochen, Engel Christoph, Hasenclever Dirk, Scholz Markus, Ahnert Peter, Kirsten Holger, Hemprich Alexander, Wittekind Christian, Herbarth Olf, Horn Friedemann, Dietz Andreas, Loeffler Markus

Abstract excerpt

Stratification of head and neck squamous cell carcinomas (HNSCC) based on HPV16 DNA and RNA status, gene expression patterns, and mutated candidate genes may facilitate patient treatment decision. We characterize head and neck squamous cell carcinomas (HNSCC) with different HPV16 DNA and RNA (E6*I) status from 290 consecutively recruited patients by gene expression profiling and targeted sequencing of 50 genes....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26095926
DOI: 10.1002/ijc.29649

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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