Article
Biological and clinical relevance of transcriptionally active human papillomavirus (HPV) infection in oropharynx squamous cell carcinoma.
International journal of cancer - 15 Apr 2010
Jung Alain C, Briolat Jenny, Millon Régine, de Reyniès Aurélien, Rickman David, Thomas Emilie, Abecassis Joseph, Clavel Christine, Wasylyk Bohdan
Abstract excerpt
Human papillomaviruses (HPV) are associated with a subset of head and neck squamous cell carcinoma (HNSCC), particularly HPV16. This study analyzed the presence and genotype of high risk HPVs, viral DNA load and transcription of the E6/E7 mRNAs, in 231 consecutive HNSCC. Twelve out of 30 HPV16 DN...
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