Article
Tail-flick test response in 3×Tg-AD mice at early and advanced stages of disease.
Neuroscience letters - 23 Jul 2015
Baeta-Corral Raquel, Defrin Ruti, Pick Chagi G, Giménez-Llort Lydia
Abstract excerpt
Despite the impact of pain in cognitive dysfunctions and affective disorders has been largely studied, the research that examines pain dimensions in cognitive impairment or dementia is still scarce. In patients with Alzheimer's disease (AD) and related dementias, management of pain is challenging. While the sensory-discriminative dimension of pain is preserved, the cognitive-evaluative and the...
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