Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Could Altered Evoked Pain Responsiveness Be a Phenotypic Biomarker for Alzheimer's Disease Risk? A Cross-Sectional Analysis of Cognitively Healthy Individuals.

Journal of Alzheimer's disease : JAD - 1 Jan 2021

Romano Raymond R, Carter Michael A, Dietrich Mary S, Cowan Ronald L, Bruehl Stephen P, Monroe Todd B

Abstract excerpt

BACKGROUND: This study evaluated whether the apolipoprotein ɛ4 (APOE4) allele, a genetic marker associated with increased risk of developing late-onset Alzheimer's disease (AD), was associated with differences in evoked pain responsiveness in cognitively healthy subjects. OBJECTIVE: The aim was to determine whether individuals at increased risk of late-onset AD based on APOE allele genotype differ phenotypically...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Alzheimer Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Apolipoprotein E4

Share to Biomarkers

Share to Cross-Sectional Studies

Share to Genetic Association Studies

Share to Hot Temperature

Share to Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 33337380
DOI: 10.3233/JAD-201293
PMCID: PMC7990440

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Could Altered Evoked Pain Responsiveness Be a Phenotypic Biomarker for Alzheimer's Disease Risk? A Cross-Sectional Analysis of Cognitively Healthy Individuals.PMID 33337380Read ↗

Tail-flick test response in 3×Tg-AD mice at early and advanced stages of disease.Semantic proximity Read ↗

Experimental Pain Phenotype Profiles in Community-dwelling Older Adults.Semantic proximity Read ↗

High-impact pain predicts subjective cognitive decline and interacts with APOE4 genotype in the development of objective cognitive impairment.Semantic proximity Read ↗

[Pain and cognitive impairment: from sensory indifference to neurodegenerative phenotype].Semantic proximity Read ↗

Reduced thermal sensitivity and increased opioidergic tone in the TASTPM mouse model of Alzheimer's disease.Semantic proximity Read ↗

Genetic components of human pain sensitivity: a protocol for a genome-wide association study of experimental pain in healthy volunteersSemantic proximity Read ↗

Abnormal pain perception is associated with thalamo-cortico-striatal atrophy in C9orf72 expansion carriers in the GENFI cohort.Semantic proximity Read ↗

Individuals at risk for Alzheimer's disease show differential patterns of ERP brain activation during odor identification.Semantic proximity Read ↗

Experimental pain phenotype profiles in a racially and ethnically diverse sample of healthy adults.Semantic proximity Read ↗

Sound-evoked auditory neurophysiological signals are a window into prodromal functional differences in a preclinical model of Alzheimer′s DiseaseSemantic proximity Read ↗

High-Impact Pain Predicts Incidence of Subjective and Objective Cognitive DeclineSemantic proximity Read ↗

Auditory hedonic phenotypes in dementia: A behavioural and neuroanatomical analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.