Article
Persistence of behaviours in the Forced Swim Test in 3xTg-AD mice at advanced stages of disease.
Behavioural processes - 1 Jul 2014
Torres-Lista Virginia, Giménez-Llort Lydia
Abstract excerpt
Forced Swimming Test (FST) models behavioural despair in animals by loss of motivation to respond or the refusal to escape. The present study characterizes the behavioural responses of 12-month-old male 3xTg-AD mice in FST as compared to age-matched no-transgenic (NTg) mice. Paradoxical results were consistently found from what would be expected from their BPSD (Behavioural and Psychological Symptoms of...
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