Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Age and gender differences for the behavioral phenotypes of 3xTg alzheimer's disease mice.

Brain research - 1 Jul 2021

Pairojana Tanita, Phasuk Sarayut, Suresh Pavithra, Huang Shun-Ping, Pakaprot Narawut, Chompoopong Supin, Hsieh Tsung-Cheng, Liu Ingrid Y

Abstract excerpt

The triple transgenic Alzheimer's disease (3xTg-AD) strain is a common mouse model used for studying the pathology and mechanism of Alzheimer's disease (AD). The 3xTg-AD strain exhibits two hallmarks of AD, amyloid beta (Aβ) and neurofibrillary tangles. Several studies using different gender and age of 3xTg-AD mice to investigate their behavior phenotypes under the influence of various treatments have reported...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age Factors
Share to Alzheimer Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Avoidance Learning

Share to Locomotion

Share to Maze Learning

Share to Mice, Transgenic

Share to Sex Characteristics

Source

Identifiers

PMID: 33753066
DOI: 10.1016/j.brainres.2021.147437

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Age and gender differences for the behavioral phenotypes of 3xTg alzheimer's disease mice.PMID 33753066Read ↗

Age-dependent phenotypic characteristics of a triple transgenic mouse model of Alzheimer disease.Semantic proximity Read ↗

Cognitive and non-cognitive behaviors in the triple transgenic mouse model of Alzheimer's disease expressing mutated APP, PS1, and Mapt (3xTg-AD).Semantic proximity Read ↗

Behavioral impairment of APP(V717F) mice in fear conditioning: is it only cognition?Semantic proximity Read ↗

Sex Differences in Behavior and Molecular Pathology in the 5XFAD Model.Semantic proximity Read ↗

A Shortened Barnes Maze Protocol Reveals Memory Deficits at 4-Months of Age in the Triple-Transgenic Mouse Model of Alzheimer's DiseaseSemantic proximity Read ↗

Environmental enrichment eliminates the anxiety phenotypes in a triple transgenic mouse model of Alzheimer's disease.Semantic proximity Read ↗

Early Spatial Memory Impairment in a Double Transgenic Model of Alzheimer’s Disease TgF-344 ADSemantic proximity Read ↗

The behavioral, pathological and therapeutic features of the triple transgenic Alzheimer's disease (3 × Tg-AD) mouse model strainSemantic proximity Read ↗

Sex differences in behaviour and molecular pathology in the 5XFAD modelSemantic proximity Read ↗

Behavioral characterization of the Tg2576 transgenic model of Alzheimer's disease through 19 months.Semantic proximity Read ↗

[Selected mice models based on APP, MAPT and presenilin gene mutations in research on the pathogenesis of Alzheimer's disease].Semantic proximity Read ↗

Anxiety in Alzheimer's disease rats is independent of memory and impacted by genotype, age, sex, and exercise.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.