Functions of Shp2 in cancer.

doi:10.1111/jcmm.12618

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Article

Functions of Shp2 in cancer.

Journal of cellular and molecular medicine - 1 Sept 2015

Zhang Jie, Zhang Fei, Niu Ruifang

Abstract excerpt

Diagnostics and therapies have shown evident advances. Tumour surgery, chemotherapy and radiotherapy are the main techniques in treat cancers. Targeted therapy and drug resistance are the main focus in cancer research, but many molecular intracellular mechanisms remain unknown. Src homology region 2-containing protein tyrosine phosphatase 2 (Shp2) is associated with breast cancer, leukaemia, lung cancer, liver...

Topics

Animals
Apoptosis
DNA Damage
Drug Resistance, Neoplasm
Humans
Mutation
Neoplasms
Protein Tyrosine Phosphatase, Non-Receptor Type 11

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Open in PubMed Open full text

Identifiers

PMID: 26088100
DOI: 10.1111/jcmm.12618
PMCID: PMC4568912

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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