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Article

Estimating the Fitness Effects of New Mutations in the Wild Yeast Saccharomyces paradoxus.

Genome biology and evolution - 16 Jun 2015

Koufopanou Vassiliki, Lomas Susan, Tsai Isheng J, Burt Austin

Abstract excerpt

The nature of selection acting on a population is in large measure determined by the distribution of fitness effects of new mutations. In this study, we use DNA sequences from four closely related clades of Saccharomyces paradoxus and Saccharomyces cerevisiae to identify and polarize new mutations and estimate their fitness effects. By progressively restricting the analyses to narrower categories of sites, we...

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Identifiers

PMID: 26085542
DOI: 10.1093/gbe/evv112
PMCID: PMC4524479

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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