Article
Genome-Wide Meta-Analysis of Longitudinal Alcohol Consumption Across Youth and Early Adulthood.
Twin research and human genetics : the official journal of the International Society for Twin Studies - 1 Aug 2015
Adkins Daniel E, Clark Shaunna L, Copeland William E, Kennedy Martin, Conway Kevin, Angold Adrian, Maes Hermine, Liu Youfang, Kumar Gaurav, Erkanli Alaattin, Patkar Ashwin A, Silberg Judy, Brown Tyson H, Fergusson David M, Horwood L John, Eaves Lindon, van den Oord Edwin J C G, Sullivan Patrick F, Costello E J
Abstract excerpt
The public health burden of alcohol is unevenly distributed across the life course, with levels of use, abuse, and dependence increasing across adolescence and peaking in early adulthood. Here, we leverage this temporal patterning to search for common genetic variants predicting developmental trajectories of alcohol consumption. Comparable psychiatric evaluations measuring alcohol consumption were collected in...
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