Article
Characterization of genetic alteration patterns in human esophageal squamous cell carcinoma using selected microsatellite markers spanning multiple loci.
International journal of oncology - 1 May 2007
Cai Yuyang Christine, So Chi K, Nie Alex Yan, Song Yunlong, Yang Guang-Yu, Wang Li-Dong, Zhao Xin, Kinzy Terri Goss, Yang Chung S
Abstract excerpt
In order to identify representative genetic alterations in esophageal squamous cell carcinomas (ESCC) and useful markers for future early detection, 34 ESCC samples with neighboring normal epithelia and 30 esophageal biopsy samples from Linzhou, P.R. China, were studied. Of the 38 microsatellite markers selected, half were linked with tumor suppressors. More than 40% of the tumor samples showed loss of...
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