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Article

Allelic imbalances and homozygous deletion on 8p23.2 for stepwise progression of hepatocarcinogenesis.

Hepatology (Baltimore, Md.) - 1 Feb 2009

Midorikawa Yutaka, Yamamoto Shogo, Tsuji Shingo, Kamimura Naoko, Ishikawa Shumpei, Igarashi Hisaki, Makuuchi Masatoshi, Kokudo Norihiro, Sugimura Haruhiko, Aburatani Hiroyuki

Abstract excerpt

UNLABELLED: Early hepatocellular carcinoma (eHCC) originates from the hepatocytes of chronic liver disease and develops into classical hepatocellular carcinoma (HCC). To identify sequential genetic changes in multistep hepatocarcinogenesis, we analyzed molecular karyotypes using oligonucleotide genotyping 50K arrays. First, 1q21.3-44 gain and loss of heterozygosity (LOH) on 1p36.21-36.32 and 17p13.1-13.3 were...

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PMID: 19105209
DOI: 10.1002/hep.22698

Genes

CSMD1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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