Article
Mutation of Kinesin-6 Kif20b causes defects in cortical neuron polarization and morphogenesis.
Neural development - 31 Mar 2017
McNeely Katrina C, Cupp Timothy D, Little Jessica Neville, Janisch Kerstin M, Shrestha Ayushma, Dwyer Noelle D
Abstract excerpt
BACKGROUND: How neurons change their cytoskeleton to adopt their complex polarized morphology is still not understood. Growing evidence suggests that proteins that help build microtubule structures during cell division are also involved in building and remodeling the complex cytoskeletons of neurons. Kif20b (previously called MPP1 or Mphosph1) is the most divergent member of the Kinesin-6 family of "mitotic"...
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