Article

A systems-level proteomic analysis identifies kinesin targets of KIFBP during neuronal development

2026-07-20

Abstract excerpt

<h4>ABSTRACT</h4> Kinesins are molecular motor proteins essential for organizing and remodeling the cytoskeleton during neuronal development and maintenance. One key regulator is kinesin family binding protein (KIFBP), which inhibits a subset of kinesins by blocking motor-microtubule interactions. Homozygous mutations in KIFBP cause Goldberg-Shprintzen Syndrome (GOSHS), a neurodevelopmental disorder characterized...

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Literature Corpus work: 93cdbbc7-5753-5575-b9ed-65fa2cf72f6a
DOI: 10.64898/2026.07.17.739260

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