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Article

Whole-mount imaging of mouse embryo sensory axon projections.

Journal of visualized experiments : JoVE - 9 Dec 2014

O'Donovan Kevin J, O'Keeffe Catherine, Zhong Jian

Abstract excerpt

The visualization of full-length neuronal projections in embryos is essential to gain an understanding of how mammalian neuronal networks develop. Here we describe a method to label in situ a subset of dorsal root ganglion (DRG) axon projections to assess their phenotypic characteristics using several genetically manipulated mouse lines. The TrkA-positive neurons are nociceptor neurons, dedicated to the...

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Identifiers

PMID: 25549235
DOI: 10.3791/52212
PMCID: PMC4299441

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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