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Article

A Systematic Approach to Identify Markers of Distinctly Activated Human Macrophages

27 May 2015

Abstract excerpt

Polarization has been a useful concept for describing activated macrophage phenotypes and gene expression profiles. However, macrophage activation status within tumors and other settings are often inferred based on only a few markers. Complicating matters for relevance to human biology, many macrophage activation markers have been best characterized in mice and sometimes are not similarly regulated in human...

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PMID: 26074920
DOI: 10.3389/fimmu.2015.00253

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