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Article

Transmitted Extended-Spectrum Extensively Drug-Resistant Tuberculosis in Beijing, China, with Discordant Whole-Genome Sequencing Analysis Results.

Journal of clinical microbiology - 1 Aug 2015

Li Hao, Kayani Masood ur Rehman, Gu Yunting, Wang Xiaobo, Zhu Ting, Duan Hongfei, Ma Yifeng, Huang Hairong, Javid Babak

Abstract excerpt

Drug resistance to tuberculosis remains a major public health threat. Here, we report two cases of extended-spectrum extensively drug-resistant (XXDR) tuberculosis showing resistance to most first- and second-line agents. The results of a correlation of whole-genome sequencing (WGS) and phenotypic testing were discordant, suggesting that overreliance on WGS may miss clinically relevant resistance in extensively...

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Identifiers

PMID: 26063862
DOI: 10.1128/JCM.00891-15
PMCID: PMC4508398

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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