Article
Genetic analysis of common variants in the HDAC2 gene with schizophrenia susceptibility in Han Chinese.
Journal of human genetics - 1 Sept 2015
Chen Gang, Guan Fanglin, Lin Huali, Li Lu, Fu Dongke
Abstract excerpt
Schizophrenia (SCZ) is a complex psychiatric disorder that is strongly influenced by a genetic component. Recent studies suggested that histone deacetylases (HDACs) might increase the expression of several key genes in the brain and may also be associated with susceptibility to SCZ. Among human HDACs, HDAC2 is a critical modulator of gene regulation. Here, we designed a two-stage case-control study to thoroughly...
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