Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evaluation of genetic susceptibility of common variants in CACNA1D with schizophrenia in Han Chinese.

Scientific reports - 10 Aug 2015

Guan Fanglin, Li Lu, Qiao Chuchu, Chen Gang, Yan Tinglin, Li Tao, Zhang Tianxiao, Liu Xinshe

Abstract excerpt

The heritability of schizophrenia (SCZ) has been estimated to be as high as 80%, suggesting that genetic factors may play an important role in the etiology of SCZ. Cav1.2 encoded by CACNA1C and Cav1.3 encoded by CACNA1D are dominant calcium channel-forming subunits of L-type Voltage-dependent Ca(2+) channels, expressed in many types of neurons. The CACNA1C has been consistently found to be a risk gene for SCZ,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to Calcium Channels, L-Type

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Haplotypes

Share to Linkage Disequilibrium

Share to Odds Ratio

Share to Schizophrenia

Source

Open in PubMed Open full text

Identifiers

PMID: 26255836
DOI: 10.1038/srep12935
PMCID: PMC4530443

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evaluation of genetic susceptibility of common variants in CACNA1D with schizophrenia in Han Chinese.PMID 26255836Read ↗

Genetic risk between the CACNA1I gene and schizophrenia in Chinese Uygur population.Semantic proximity Read ↗

Evaluating the association between CACNA1C rs1006737 and schizophrenia risk: A meta-analysis.Semantic proximity Read ↗

Further evidence for the genetic association between CACNA1I and schizophrenia.Semantic proximity Read ↗

Further evidence for genetic association of CACNA1C and schizophrenia: new risk loci in a Han Chinese population and a meta-analysis.Semantic proximity Read ↗

Identification of ultra-rare disruptive variants in voltage-gated calcium channel-encoding genes in Japanese samples of schizophrenia and autism spectrum disorder.Semantic proximity Read ↗

Role of CACNA1C gene polymorphisms and protein expressions in the pathogenesis of schizophrenia: a case-control study in a Chinese population.Semantic proximity Read ↗

CACNA1C, schizophrenia and major depressive disorder in the Han Chinese population.Semantic proximity Read ↗

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects.Semantic proximity Read ↗

Genome-wide association analysis identifies 13 new risk loci for schizophrenia.Semantic proximity Read ↗

Association of CACNA1C polymorphisms (rs1006737, rs4765905, rs2007044) with schizophrenia: A meta-analysis and trial sequential analysis.Semantic proximity Read ↗

Association analysis of CHRNA3 polymorphisms with schizophrenia in a Chinese Han population: A case-control study.Semantic proximity Read ↗

Schizophrenia Related Variants in CACNA1C also Confer Risk of Autism.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.