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Article

Two-stage additional evidence support association of common variants in the HDAC3 with the increasing risk of schizophrenia susceptibility.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Dec 2016

Jia Xiaodi, Zhang Tianxiao, Li Lu, Fu Dongke, Lin Huali, Chen Gang, Liu Xinshe, Guan Fanglin

Abstract excerpt

Schizophrenia (SCZ) is a complex neuropsychiatric disorder with high heritability. Abnormal gene methylation was found to play a key role in the development of SCZ, suggesting that histone deacetylases (HDACs) may increase the expression of several key genes in the brain. However, recent studies evaluating the association between SCZ and genetic polymorphisms in histone deacetylase 3 (encoded by HDAC3) have shown...

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Identifiers

PMID: 27573569
DOI: 10.1002/ajmg.b.32491

Genes

HDAC3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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