Article
JNK signalling is necessary for a Wnt- and stem cell-dependent regeneration programme.
Development (Cambridge, England) - 15 Jul 2015
Tejada-Romero Belen, Carter Jean-Michel, Mihaylova Yuliana, Neumann Bjoern, Aboobaker A Aziz
Abstract excerpt
Regeneration involves the integration of new and old tissues in the context of an adult life history. It is clear that the core conserved signalling pathways that orchestrate development also play central roles in regeneration, and further study of conserved signalling pathways is required. Here we have studied the role of the conserved JNK signalling cascade during planarian regeneration. Abrogation of JNK...
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