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Article

The molecular logic for planarian regeneration along the anterior-posterior axis.

Nature - 1 Aug 2013

Umesono Yoshihiko, Tasaki Junichi, Nishimura Yui, Hrouda Martina, Kawaguchi Eri, Yazawa Shigenobu, Nishimura Osamu, Hosoda Kazutaka, Inoue Takeshi, Agata Kiyokazu

Abstract excerpt

The planarian Dugesia japonica can regenerate a complete individual from a head, trunk or tail fragment via activation of somatic pluripotent stem cells. About a century ago, Thomas Hunt Morgan attempted to explain the extraordinary regenerative ability of planarians by positing two opposing morphogenetic gradients of formative "head stuff" and "tail stuff" along the anterior-posterior axis. However, Morgan's...

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PMID: 23883928
DOI: 10.1038/nature12359

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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