Article
The Drosophila Jun-N-terminal kinase is required for cell morphogenesis but not for DJun-dependent cell fate specification in the eye.
Genes & development - 1 Nov 1996
Riesgo-Escovar J R, Jenni M, Fritz A, Hafen E
Abstract excerpt
We cloned and characterized the Drosophila homolog of mammalian Jun-N-terminal kinases (DJNK). We show that DJNK is encoded by basket (bsk). Like hemipterous (hep), which encodes the Drosophila JNK kinase, bsk is required in the embryo for dorsal closure, a process involving coordinate cell shape changes of ectodermal cells. Dorsal closure can also be blocked by dominant negative Drosophila cdc42, which has been...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.