Article
The Drosophila Jun-N-terminal kinase is required for cell morphogenesis but not for DJun-dependent cell fate specification in the eye.
Genes & development - 1 Nov 1996
Riesgo-Escovar J R, Jenni M, Fritz A, Hafen E
Abstract excerpt
We cloned and characterized the Drosophila homolog of mammalian Jun-N-terminal kinases (DJNK). We show that DJNK is encoded by basket (bsk). Like hemipterous (hep), which encodes the Drosophila JNK kinase, bsk is required in the embryo for dorsal closure, a process involving coordinate cell shape...
Topics
- Amino Acid Sequence
- Animals
- Cell Lineage
- Drosophila
- Drosophila Proteins
- Eye
- Gene Expression Regulation, Developmental
- Gene Expression Regulation, Enzymologic
- Genes, Dominant
- Mitogen-Activated Protein Kinase Kinases
- Molecular Sequence Data
- Morphogenesis
- Mutation
- Phenotype
- Protein Kinases
- Sequence Homology, Amino Acid