Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phosphorylation of myosin regulatory light chain controls myosin head conformation in cardiac muscle

7 Jun 2015

Abstract excerpt

The effect of phosphorylation on the conformation of the regulatory light chain (cRLC) region of myosin in ventricular trabeculae from rat heart was determined by polarized fluorescence from thiophosphorylated cRLCs labelled with bifunctional sulforhodamine (BSR). Less than 5% of cRLCs were endogenously phosphorylated in this preparation, and similarly low values of basal cRLC phosphorylation were measured in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiomyopathy and Myosin Studies
Share to Cardiovascular Effects of Exercise
Share to Muscle Physiology and Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26057075
DOI: 10.1016/j.yjmcc.2015.06.002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phosphorylation of myosin regulatory light chain controls myosin head conformation in cardiac musclePMID 26057075Read ↗

The role of myosin regulatory light chain phosphorylation in cardiac health and diseaseSemantic proximity Read ↗

Phosphorylation of the regulatory light chain of myosin in striated muscle: methodological perspectivesSemantic proximity Read ↗

The structural and functional effects of myosin regulatory light chain phosphorylation are amplified by increases in sarcomere length and [Ca 2+ ]Semantic proximity Read ↗

Structural and functional responses of mammalian thick filaments to alterations in myosin regulatory light chains.Semantic proximity Read ↗

Signaling to Myosin Regulatory Light Chain in SarcomeresSemantic proximity Read ↗

Site-directed spin labeling reveals a conformational switch in the phosphorylation domain of smooth muscle myosin.Semantic proximity Read ↗

Expression of a myosin regulatory light chain phosphorylation site mutant complements the cytokinesis and developmental defects of Dictyostelium RMLC null cells.Semantic proximity Read ↗

Regulatory light chain mutants linked to heart disease modify the cardiac myosin lever arm.Semantic proximity Read ↗

Myosin regulatory domain orientation in skeletal muscle fibers: application of novel electron paramagnetic resonance spectral decomposition and molecular modeling methods.Semantic proximity Read ↗

Myosin cross-bridges do not form precise rigor bonds in hypertrophic heart muscle carrying troponin T mutations.Semantic proximity Read ↗

Familial hypertrophic cardiomyopathy can be characterized by a specific pattern of orientation fluctuations of actin molecules .Semantic proximity Read ↗

Coupling of ATPase activity and motility in smooth muscle myosin is mediated by the regulatory light chain.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.