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Article

Epigenetics and systemic sclerosis.

Seminars in immunopathology - 1 Sept 2015

Altorok Nezam, Kahaleh Bashar

Abstract excerpt

Systemic sclerosis (SSc) is an autoimmune connective tissue disease characterized by vascular injury, activation of the immune system, and diffuse tissue fibrosis. The precise etiology of SSc is undetermined, but there is evidence suggestive of a connection between environmental factors and SSc pathogenesis. In general, harmful environmental factors are sensed by the epigenetic regulatory mechanisms that alter...

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Share to DNA Methylation
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Share to Gene Expression Regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Scleroderma, Systemic

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Source

Identifiers

PMID: 26162437
DOI: 10.1007/s00281-015-0504-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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