Article
Glucose Metabolism in High-Risk Subjects for Type 2 Diabetes Carrying the rs7903146 TCF7L2 Gene Variant.
The Journal of clinical endocrinology and metabolism - 1 Aug 2015
Daniele Giuseppe, Gaggini Melania, Comassi Mario, Bianchi Cristina, Basta Giuseppina, Dardano Angela, Miccoli Roberto, Mari Andrea, Gastaldelli Amalia, Del Prato Stefano
Abstract excerpt
CONTEXT: The mechanisms responsible for contribution of variants in the gene TFC7L2 to the risk for type 2 diabetes (T2DM) remains far from being completely understood, and available studies have generated nonunivocal results. OBJECTIVE: We investigated the postprandial glucose metabolism in subjects at risk for T2DM carrying the TCF7L2 risk allele. DESIGN, SETTING, AND PARTICIPANTS: Twenty-three subjects...
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