Article
TCF7L2, dietary carbohydrate, and risk of type 2 diabetes in US women.
The American journal of clinical nutrition - 1 Apr 2009
Cornelis Marilyn C, Qi Lu, Kraft Peter, Hu Frank B
Abstract excerpt
BACKGROUND: TCF7L2 is the strongest type 2 diabetes (T2D) locus identified to date, and evidence suggests it plays an important role in insulin synthesis, processing, and secretion. Dietary factors that increase the insulin demand might enhance the risk of T2D associated with TCF7L2 variants. OBJECTIVE: The objective was to determine whether the risk of T2D associated with TCF7L2 is modified by the glycemic load...
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