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Article

Genetics of Bone Mass in Childhood and Adolescence: Effects of Sex and Maturation Interactions.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Sept 2015

Mitchell Jonathan A, Chesi Alessandra, Elci Okan, McCormack Shana E, Kalkwarf Heidi J, Lappe Joan M, Gilsanz Vicente, Oberfield Sharon E, Shepherd John A, Kelly Andrea, Zemel Babette S, Grant Struan F A

Abstract excerpt

We aimed to determine if adult bone mineral density (BMD) susceptibility loci were associated with pediatric bone mass and density, and if sex and pubertal stage influenced any association. We analyzed prospective areal BMD (aBMD) and bone mineral content (BMC) data from the Bone Mineral Density in Childhood Study (n = 603, European ancestry, 54% female). Linear mixed models were used to assess if 77...

Topics

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Bone and Bones
Bone Density
Bone Development
Calcium, Dietary

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Fractures, Bone

Low Density Lipoprotein Receptor-Related Protein-5

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Open in PubMed Open full text

Identifiers

PMID: 25762182
DOI: 10.1002/jbmr.2508
PMCID: PMC4839534

Genes

LRP5
WNT16

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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