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Article

Association of Polymorphisms in Innate Immunity Genes TLR9 and DEFB1 with Human Longevity.

Bulletin of experimental biology and medicine - 1 May 2015

Gankovskaya L V, Svitich O A, Artem'eva O V, Miroshnichenkova A M, Rusanova K V

Abstract excerpt

The distribution of polymorphic variants of innate immunity genes TLR9 (+2848G>A) and DEFB1(-20G>A; -44C>G; -52G>A) was evaluated in long-living individuals. No significant differences were found in the distribution of genotypes and alleles of the TLR9 gene. The following features were revealed: increase in the frequency of AA and GG genotypes and decrease in the frequency of the AG genotype of the DEFB1(-20G>A)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26028230
DOI: 10.1007/s10517-015-2894-9

Genes

DEFB1
TLR9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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