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Article

Association between TLR 2 (rs3804099), TLR4 (rs4986790), and TLR 9 (rs187084) polymorphism and leukemia risk: a systematic review and meta-analysis.

Immunologic research - 16 Jan 2025

Kumar Rupesh, Dutta Anindita, Phukan Mayur Mausoom

Abstract excerpt

Toll-like receptors (TLRs) are crucial components of innate immunity. A specific form of genetic variation in TLR genes may increase the chance of developing leukemia. The present investigation conducted a comprehensive meta-analysis to examine the correlation between three TLR polymorphisms, namely TLR2 (rs3804099), TLR4 (rs4986790), and TLR9 (rs187084), within the leukemia risk group. An in-depth literature...

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Share to Genetic Association Studies
Share to Genetic Predisposition to Disease
Share to Leukemia
Share to Polymorphism, Single Nucleotide
Share to Risk Factors
Share to Toll-Like Receptor 2
Share to Toll-Like Receptor 4
Share to Toll-Like Receptor 9

Source

Identifiers

PMID: 39815014
DOI: 10.1007/s12026-025-09592-y

Genes

TLR2
TLR4
TLR9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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