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Article

Using genomic annotations increases statistical power to detect eGenes.

Bioinformatics (Oxford, England) - 15 Jun 2016

Duong Dat, Zou Jennifer, Hormozdiari Farhad, Sul Jae Hoon, Ernst Jason, Han Buhm, Eskin Eleazar

Abstract excerpt

MOTIVATION: Expression quantitative trait loci (eQTLs) are genetic variants that affect gene expression. In eQTL studies, one important task is to find eGenes or genes whose expressions are associated with at least one eQTL. The standard statistical method to determine whether a gene is an eGene requires association testing at all nearby variants and the permutation test to correct for multiple testing. The...

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Identifiers

PMID: 27307612
DOI: 10.1093/bioinformatics/btw272
PMCID: PMC4908356

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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