APOL1 G1 genotype modifies the association between HDLC and kidney function in African Americans.

doi:10.1186/s12864-015-1645-7

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Article

APOL1 G1 genotype modifies the association between HDLC and kidney function in African Americans.

BMC genomics - 30 May 2015

Bentley Amy R, Divers Jasmin, Shriner Daniel, Doumatey Ayo P, Gutiérrez Orlando M, Adeyemo Adebowale A, Freedman Barry I, Rotimi Charles N

Abstract excerpt

BACKGROUND: Despite evidence of an association between variants at the apolipoprotein L1 gene (APOL1) locus and a spectrum of related kidney diseases, underlying biological mechanisms remain unknown. An earlier preliminary study published by our group showed that an APOL1 variant (rs73885319) modified the association between high-density lipoprotein cholesterol (HDLC) and estimated glomerular filtration rate...

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Identifiers

PMID: 26025194
DOI: 10.1186/s12864-015-1645-7
PMCID: PMC4448293

Genes

APOL1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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