Article
Genetic polymorphisms in Toll-like receptor 3 gene are associated with the risk of hepatitis B virus-related liver diseases in a Chinese population.
Gene - 15 Sept 2015
Huang Xiamei, Li Haiwei, Wang Jian, Huang Chunni, Lu Yu, Qin Xue, Li Shan
Abstract excerpt
Toll-like receptors (TLRs) are well known to play a critical role in antiviral and antitumor response. Available evidence has demonstrated that TLRs are implicated in the immunopathogenesis of hepatitis B virus (HBV) infection and tumor carcinogenesis. Therefore, we performed the present study to...
Topics
- Asian People
- Carcinoma, Hepatocellular
- Genetic Predisposition to Disease
- Hepatitis B virus
- Hepatitis B, Chronic
- Humans
- Liver Cirrhosis
- Liver Neoplasms
- Polymorphism, Single Nucleotide
- Toll-Like Receptor 3