Article
Toll-like receptor 3 polymorphism and its association with hepatitis B virus infection in Saudi Arabian patients.
Journal of medical virology - 1 Sept 2012
Al-Qahtani Ahmed, Al-Ahdal Mohammed, Abdo Ayman, Sanai Faisal, Al-Anazi Mashael, Khalaf Nisreen, Viswan Nisha A, Al-Ashgar Hamad, Al-Humaidan Hind, Al-Suwayeh Riham, Hussain Zahid, Alarifi Saud, Al-Okail Majid, Almajhdi Fahad N
Abstract excerpt
Hepatitis B virus (HBV) is the major causative agent of chronic liver complications including cirrhosis and hepatocellular carcinoma (HCC). Individuals infected with HBV show a wide spectrum of disease manifestations ranging from asymptomatic carriers to HCC. TLR3 is part of the innate immune system that recognizes double-stranded RNA (dsRNA) and provides early immune response to exogenous antigens. The genetic...
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