Investigation of 1377C/T polymorphism of the Toll-like receptor 3 among patients with chronic hepatitis B.

doi:10.1139/cjm-2016-0129

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Article

Investigation of 1377C/T polymorphism of the Toll-like receptor 3 among patients with chronic hepatitis B.

Canadian journal of microbiology - 1 Jul 2016

Goktas Emine Firat, Bulut Cemal, Goktas Mustafa Tugrul, Ozer Erdem Kamil, Karaca Ragip Ozgur, Kinikli Sami, Demiroz Ali Pekcan, Bozkurt Atilla

Abstract excerpt

The immunopathogenesis of chronic hepatitis B (CHB) has not been clarified yet. Toll-like receptors (TLR) are a receptor family that initiates immunity with exogenous-endogenous ligands and plays a role in the pathogenesis of infections. In this study, we aimed to investigate the frequency of TLR 3 1377C/T (rs3775290) polymorphism and its role in patients with CHB. We included 50 healthy individuals as control...

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PMID: 27314608
DOI: 10.1139/cjm-2016-0129

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