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Article

Study of Toll-like Receptor 3 Gene Polymorphism as a Novel Risk Factor for HCV-related Hepatocellular Carcinoma in Egypt.

Current cancer drug targets - 1 Jan 2020

El-Sharawy Shimaa, Negm Osama El-Sayed, Abd-Elsalam Sherief, El-Sorogy Hesham Ahmed, Shehata Mona Ahmed Helmy

Abstract excerpt

BACKGROUND AND AIMS: Hepatocellular carcinoma (HCC) is a highly aggressive cancer with few treatment options. Toll-like receptor 3 (TLR3) plays a key role in innate immunity and may affect the development of cancers. This study aimed to investigate the association between TLR3 gene polymorphism and HCV-related hepatocellular carcinoma in Egypt. METHODS: This work was conducted on 70 individuals; fifty HCV...

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Identifiers

PMID: 32189594
DOI: 10.2174/1568009620666200319102929

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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